Relief may require only a $4 generic.

Acute migraine headaches may be stopped or often reduced in intensity with beta blocker eye drops, the widely available glaucoma medication that costs as little as $4 per bottle, according to John C. Hagan III, MD and Carl V. Migliazzo, MD, both of Kansas City, Mo. The pair have published a study of seven acute migraines patients treated over a multi-year period.¹ While the daily use of beta blocker pills has proved effective in preventing chronic migraine headaches, they have been unsuccessful in treating acute, sudden-onset migraines. Beta-blocker eye drops, however, are absorbed more quickly than pills by tear duct drainage onto the nasal mucosa, the investigators say, achieving therapeutic plasma levels “within minutes.”

Drs. Hagan and Migliazzo note that their study is small, selective and retrospective — all seven of the case studies involved female patients, for instance — and as their peer reviewers pointed out, controlled prospective studies are needed. The University of Kansas